Is It Your Genes?
🧬 Genetic SNP Summary – Function & Associated Symptoms
GeneFunction / AssociationCommon Symptoms
MTHFR (C677T)🧬 Folate metabolism, homocysteine levels⚡ Fatigue, ❤️ Cardiovascular risk, 😔 Depression, 🫀 Heart disease, 🧠 Stroke, 🤰 Miscarriage
MTHFR (A1298C)🧠 Neurotransmitter synthesis😟 Anxiety, 😞 Mood issues, 🧠 Neurotransmitter imbalance
COMT⚡ Dopamine metabolism, anxiety😰 Stress intolerance, 😡 Irritability
APOE🧠 Alzheimer's risk, lipid metabolism🧓 Higher Alzheimer's risk, 🧠 Memory loss
VDR☀️ Vitamin D receptor function🛡️ Low vitamin D, weaker immunity
FUT2🦠 Gut microbiome, B12 absorption🍽️ Digestive issues, 💊 Low B12, 🤧 Higher infection risk
IL6🔥 Inflammation, autoimmunity🛡️ Inflammation-related issues, autoimmunity
TNF🔥 TNF-alpha expression🔥 High inflammation, 🦠 Autoimmune risk
GSTT1🧹 Detoxification⚡ Oxidative stress, 🧹 Poor detox ability
GSTM1🧹 Detoxification⚡ Oxidative stress, 🧹 Poor detox ability
SOD2🔋 Antioxidant enzyme (mitochondria)🔋 Oxidative stress, 🧬 Mitochondrial issues
MAO-A🧠 Serotonin/dopamine metabolism😵 Mood swings, 😠 Irritability
HLA-DRB1🛡️ MS risk & autoimmunity🛡️ Higher MS risk, autoimmune tendencies
IL2RA🛡️ Immune regulation🛡️ Autoimmunity risk, immune imbalance
IL7R🛡️ T cell signaling🛡️ Immune dysregulation, T-cell issues
TCN2💊 Vitamin B12 transport⚡ Fatigue, 💊 B12 deficiency, 🧠 Anemia
ACE❤️ Cardiovascular health🫀 High blood pressure, heart issues
NOS3💓 Vascular function❤️ Cardiovascular risk, poor circulation
DAO🧪 Histamine degradation🤧 Histamine intolerance, GI & skin symptoms
HNMT🧪 Histamine metabolism🤕 Headaches, rashes, flushing
MAOA🧠 Mood regulation😡 Mood swings, aggression, depression
MAOA (Fast)🧠 Low serotonin/dopamine😐 Depression risk, low emotional response
MAOB🧠 Dopamine breakdown😟 Mood imbalance
ADRA2A🏃 ADHD, impulsivity🧠 Attention issues, hyperactivity
SLC6A4🧠 Serotonin transport😢 Depression, 😟 Anxiety
BDNF🌱 Neuronal growth🧠 Poor neuroplasticity, memory decline
DRD2🎯 Dopamine receptor😒 Apathy, addiction risk
DRD4🎯 Dopamine receptor🏃 ADHD-like behavior, thrill-seeking
HTR2A🧠 Serotonin receptor😢 Mood disorders, low serotonin activity
COMT (Slow)⚡ Estrogen/dopamine metabolism😰 Anxiety, 🧬 Estrogen sensitivity
COMT (Fast)⚡ Estrogen/dopamine metabolism😑 Emotional blunting, low dopamine, stress intolerance
🧬 Why Knowing Your Gene SNPs Matters
Understanding your gene SNPs (Single Nucleotide Polymorphisms) gives you a personalized roadmap to your body’s unique strengths and vulnerabilities. These tiny genetic variations can affect how you metabolize nutrients, detoxify toxins, regulate mood, process hormones, respond to stress, and defend against illness.
While your genes are fixed, your health outcomes are not. Many of the illnesses linked to these SNPs—such as cardiovascular disease, anxiety, autoimmune disorders, and even Alzheimer’s—are influenced by lifestyle and environment, not just genetics.
Through targeted supplementation, dietary adjustments, stress reduction, and toxin avoidance, you can often "turn down the volume" on problematic genes and prevent or reduce symptoms. For example:
Someone with an MTHFR variant may need methylated B vitamins to improve energy and lower homocysteine.
A person with a DAO mutation may reduce migraines and rashes by following a low-histamine diet.
Those with COMT or MAOA variants may improve mood stability by supporting dopamine metabolism through food, adaptogens, and lifestyle.
By addressing your bio-individual needs, you can move from guessing to precision—preventing illness before it starts or supporting healing where needed. This is the foundation of functional and personalized health.